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SMART on FHIR at Scale: How Enterprises Are Modernizing EHR Integration

Michael Nikitin

CTO & Co-founder AIDA, CEO Itirra

Published on May 9, 2025

SMART on FHIR at Scale: How Enterprises Are Modernizing EHR Integration

Table of Contents

1. Introduction

Healthcare enterprises are under increasing pressure to modernize their systems, improve patient care, and meet strict regulatory requirements. One of the biggest roadblocks to progress is inefficient and fragmented EHR (Electronic Health Record) integration. However, the rise of SMART on FHIR has begun to change this landscape, offering a scalable, standardized approach to data connectivity. This evolution is enabling healthcare organizations to securely integrate apps, improve workflows, and make data more accessible across systems. In this article, we explore how SMART on FHIR is being adopted at enterprise scale—and how you can follow suit. We also introduce Itirra, a Washington State-based health tech lab with over a decade of expertise in delivering bespoke EMR and EHR integration solutions for physician advisors, medical consultants, and revenue cycle management (RCM) firms.

2. Understanding SMART on FHIR

To begin with, SMART on FHIR combines two critical technologies: FHIR (Fast Healthcare Interoperability Resources), a standard for health data exchange, and SMART (Substitutable Medical Applications, Reusable Technologies), which adds security and app authorization protocols. Together, they allow healthcare apps to integrate seamlessly with existing EHR platforms while maintaining secure data flows. This powerful combination lets developers create apps that are reusable across multiple systems, reducing the need for redundant interfaces. Moreover, SMART on FHIR facilitates OAuth2-based authorization, which ensures both user authentication and secure access to patient data. As a result, enterprises gain agility without compromising compliance or performance.

3. The Scaling Challenge in EHR Integration

Historically, scaling EHR integrations across an enterprise has been a massive undertaking. Legacy systems often use proprietary APIs, inconsistent data formats, and outdated authentication protocols. This leads to a patchwork of custom code, brittle connections, and high maintenance costs. As organizations grow or merge, these issues are only magnified, creating major interoperability challenges. Fortunately, SMART on FHIR introduces a standardized method to access health data, easing the burden of scale. With this framework, enterprises can connect multiple systems and third-party apps using a consistent, extensible architecture.

4. Itirra: A Trusted Leader in Health Data Integration

While the benefits of SMART on FHIR are clear, implementation at scale demands deep technical expertise and healthcare domain knowledge. That’s where Itirra comes in. For over ten years, Itirra has helped physician advisors, RCM firms, and third-party medical consultants integrate their systems and workflows with leading EHR platforms. Their approach is both strategic and hands-on—building customized, compliant solutions tailored to each client’s needs. Whether you’re looking to build from scratch or modernize an existing product, Itirra brings the tools, insight, and experience to guide your journey. They don’t just build solutions—they build value into every integration.

5. Why Enterprises Are Moving to SMART on FHIR

There are several compelling reasons why large organizations are adopting SMART on FHIR. First, it streamlines integrations with major EHR systems like Epic, Cerner, and Allscripts. Second, it significantly reduces vendor lock-in by allowing apps to run across multiple environments with minimal rework. Additionally, the standard’s strong security model helps enterprises maintain data integrity and regulatory compliance. Transitioning to SMART on FHIR also improves operational agility, enabling faster onboarding of new tools and technologies. Altogether, these advantages make SMART on FHIR an essential part of any enterprise modernization strategy.

6. Breaking Free from Legacy Systems

One of the primary obstacles to innovation in healthcare is dependence on legacy infrastructure. These older systems often lack APIs, follow outdated data models, and require manual processes that introduce inefficiencies. Moving to SMART on FHIR allows enterprises to abstract away these limitations by building modern applications that can access and update data securely across platforms. Additionally, it helps IT teams avoid costly, time-consuming custom integrations with every new system. In doing so, organizations can accelerate digital transformation while preserving existing investments. SMART on FHIR becomes the bridge between legacy and modern health IT.

7. Standardization for Multi-System Interoperability

Enterprises often operate across multiple facilities, departments, and technologies. Without standardization, interoperability becomes almost impossible to maintain over time. By adopting SMART on FHIR, enterprises gain a common language for health data and a consistent way to authenticate users and authorize access. This allows developers to build applications once and deploy them across different EHRs with minimal modification. Furthermore, it improves collaboration across organizational silos, enabling smoother data flow between teams and systems. Ultimately, standardization is the cornerstone of scalable, sustainable integration.

8. Security, Compliance, and Control at Scale

Handling protected health information (PHI) at scale requires more than just connectivity—it requires airtight security and governance. SMART on FHIR helps meet these demands with OAuth2 protocols, scoped access tokens, and transparent consent workflows. These features give organizations control over who can access what data, when, and under what conditions. Additionally, SMART on FHIR aligns with federal initiatives such as the ONC’s Cures Act Final Rule, supporting compliance while promoting innovation. Itirra ensures that every implementation meets or exceeds these standards, providing ongoing support for audits, updates, and risk mitigation. With the right strategy, scalability doesn’t mean sacrificing control.

9. SMART on FHIR in Action: Real-World Use Cases

Across the industry, SMART on FHIR is enabling a wide range of innovative use cases. For example, hospitals are deploying clinical decision support tools that work across EHRs, while insurers are offering member portals that aggregate data from multiple providers. Additionally, RCM companies are using SMART on FHIR to automate billing workflows, improve coding accuracy, and reduce denials. In each case, the result is faster implementation, better data transparency, and improved outcomes. These real-world successes prove that SMART on FHIR isn’t just a theory—it’s a practical, powerful solution for healthcare at scale. Enterprises that adopt it today are setting themselves up for long-term success.

10. Collaborating with the Right Development Partner

Scaling SMART on FHIR requires more than just technical know-how—it requires a strategic partner who understands the unique challenges of healthcare. That’s why many enterprises turn to Itirra. Their team combines deep engineering expertise with regulatory awareness and a nuanced understanding of healthcare workflows. From planning and development to integration and deployment, they work closely with clients to ensure success at every stage. Whether you’re building a patient app, provider dashboard, or analytics engine, Itirra helps you get to market faster—with confidence. A trusted partner makes all the difference when scaling complex health systems.

11. Looking Ahead: The Future of Scalable Integration

As healthcare continues to digitize, the need for scalable, interoperable solutions will only grow. FHIR R5, artificial intelligence, and patient-centric care models will further raise the bar for integration. SMART on FHIR is a foundation that can adapt to these changes, providing a flexible framework for future-ready development. Additionally, regulatory bodies are pushing harder for data transparency and portability, making standards-based approaches not just ideal, but essential. Enterprises that invest in SMART on FHIR today are better positioned to evolve with the market. The time to modernize is now.

12. Start Scaling with SMART on FHIR Today

The shift toward scalable, interoperable EHR integration is well underway—and SMART on FHIR is leading the charge. But navigating this journey requires the right blend of strategy, experience, and execution. Itirra, with over a decade of success in healthcare integration, is uniquely positioned to help your organization modernize with confidence. From custom EHR workflows to fully compliant SMART on FHIR implementations, they’ve done it all. Don’t let legacy systems or integration roadblocks hold you back.

Contact Itirra today and take the next step toward scalable healthcare innovation.